The Johns Hopkins medical center and Applied Physics Lab needed a platform that was stable, could collect information, and dispense it to the right parties easily in a secure manner. The research center uses HDP and HDF as its data solution. Data is hugely sensitive, so security is of utmost concern. Security components such as Apache Knox, Apache Atlas, and Apache Ranger help keep data secure. Initial use case was precision medicine. HDF and Apache Nifi are used for data ingestion for patient data from various sources.